PDGFA protein

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:PDGF-A
Platelet-derived growth factor A chain
gptkbp:associatedWith gptkb:cancer
atherosclerosis
fibrosis
gptkbp:encodedBy PDGFA gene
gptkbp:form homodimer
heterodimer with PDGFB protein
gptkbp:fullName Platelet-derived growth factor subunit A
gptkbp:function mitogenic factor for cells of mesenchymal origin
stimulates cell growth, proliferation, and angiogenesis
https://www.w3.org/2000/01/rdf-schema#label PDGFA protein
gptkbp:locatedOnChromosome chromosome 7p22
gptkbp:location extracellular space
gptkbp:molecularWeight 24 kDa (monomer)
gptkbp:postTranslationalModification glycosylation
disulfide bond formation
gptkbp:recipient gptkb:PDGF_receptor_alpha
gptkb:PDGF_receptor_beta
gptkbp:UniProtID P04085
gptkbp:bfsParent gptkb:PDGFRB_protein
gptkb:Pdgfa
gptkb:PAY3
gptkbp:bfsLayer 8