Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PD-L2
gptkb:B7-DC |
| gptkbp:binds |
gptkb:PD-1
|
| gptkbp:encodedBy |
gptkb:PDCD1LG2_gene
|
| gptkbp:Entrez_Gene_ID |
ENSG00000197646
|
| gptkbp:expressedIn |
dendritic cells
macrophages some tumor cells |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
immune checkpoint ligand
|
| gptkbp:gene |
gptkb:PDCD1LG2
|
| gptkbp:HGNC_ID |
HGNC:18741
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD273
|
| gptkbp:length |
273 amino acids (human)
|
| gptkbp:locatedOnChromosome |
chromosome 9p24.1 (human)
|
| gptkbp:memberOf |
gptkb:B7_family
|
| gptkbp:relatedTo |
immunotherapy
|
| gptkbp:role |
immune tolerance
inhibition of T cell activation |
| gptkbp:structure |
type I transmembrane protein
|
| gptkbp:target |
immune checkpoint inhibitors
|
| gptkbp:UniProtID |
Q9BQ51
|
| gptkbp:bfsParent |
gptkb:PD-L2
gptkb:tumor_necrosis_factor_receptor_superfamily |
| gptkbp:bfsLayer |
7
|