|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:DJ-1
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodedBy
|
gptkb:PARK7_gene
|
|
gptkbp:Entrez_Gene_ID
|
11315
|
|
gptkbp:family
|
gptkb:DJ-1/ThiJ/PfpI_superfamily
|
|
gptkbp:function
|
antioxidant activity
chaperone activity
protein deglycase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PARK7
|
|
gptkbp:interactsWith
|
gptkb:LRRK2
gptkb:alpha-synuclein
gptkb:PINK1
|
|
gptkbp:length
|
189 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p36
|
|
gptkbp:molecularWeight
|
20 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:early-onset_Parkinson's_disease
|
|
gptkbp:OMIM
|
602533
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1P5F
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
|
|
gptkbp:role
|
cellular response to oxidative stress
transcriptional regulation
mitochondrial homeostasis
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
mitochondria
|
|
gptkbp:UniProtID
|
Q99497
|
|
gptkbp:bfsParent
|
gptkb:DJ-1
|
|
gptkbp:bfsLayer
|
7
|