|
gptkbp:instanceOf
|
gptkb:UniProt_accession_number
|
|
gptkbp:alternativeName
|
gptkb:CDK5
Cell division protein kinase 5
Serine/threonine-protein kinase PSSALRE
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Amyotrophic_lateral_sclerosis
gptkb:Parkinson's_disease
|
|
gptkbp:cofactor
|
Mg2+
|
|
gptkbp:component
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000164885
|
|
gptkbp:enzymeClassification
|
EC 2.7.11.22
|
|
gptkbp:firstPublished
|
1994
|
|
gptkbp:function
|
protein serine/threonine kinase activity
Serine/threonine-protein kinase activity
|
|
gptkbp:gene
|
gptkb:CDK5
|
|
gptkbp:GOProcess
|
cell cycle regulation
neuron migration
|
|
gptkbp:HGNC_ID
|
1771
|
|
gptkbp:interactsWith
|
p35 (CDK5R1)
p39 (CDK5R2)
|
|
gptkbp:InterPro
|
gptkb:IPR000719
|
|
gptkbp:KEGGID
|
hsa:1020
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
7q36.1
|
|
gptkbp:location
|
gptkb:Nucleus
gptkb:Cytoplasm
|
|
gptkbp:molecularWeight
|
33 kDa
|
|
gptkbp:OMIM
|
123410
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1UNL
1H4L
3O0G
|
|
gptkbp:phosphorylates
|
gptkb:Ser159
Tyr15
|
|
gptkbp:proteinFamily
|
gptkb:PF00069
|
|
gptkbp:Reactome
|
R-HSA-8866654
|
|
gptkbp:refersTo
|
Human protein: Cyclin-dependent kinase 5 (CDK5)
|
|
gptkbp:RefSeq
|
NP_001157009.1
NP_004926.1
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:sequence
|
292
|
|
gptkbp:tissue_specificity
|
gptkb:testis
brain
pancreas
|
|
gptkbp:UniGene
|
Hs.654
|
|
gptkbp:UniProt_entry_name
|
CDK5_HUMAN
|
|
gptkbp:bfsParent
|
gptkb:HK3
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P52790
|