Statements (46)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
UniProt accession number
|
| gptkbp:alternativeName |
gptkb:Peroxisome_proliferator-activated_receptor_gamma
gptkb:Gamma gptkb:NR1C3 |
| gptkbp:associatedWith |
gptkb:Lipodystrophy
gptkb:Type_2_diabetes gptkb:Insulin_resistance Obesity |
| gptkbp:biologicalProcess |
DNA-binding transcription factor activity
Regulation of glucose homeostasis Lipid metabolism Adipocyte differentiation Ligand-activated transcription factor activity |
| gptkbp:cellularComponent |
gptkb:Nucleus
|
| gptkbp:citation |
Ensembl: ENSG00000132170
GeneCards: PPARG HGNC: 9236 KEGG: hsa:5468 NCBI Gene: 5468 OMIM: 601487 Reactome: R-HSA-400206 UniProt: P28562 |
| gptkbp:database |
gptkb:UniProtKB/Swiss-Prot
|
| gptkbp:function |
Nuclear receptor regulating adipogenesis and glucose metabolism
|
| gptkbp:gene |
gptkb:PPARG
|
| https://www.w3.org/2000/01/rdf-schema#label |
P28562
|
| gptkbp:ligand |
Fatty acids
Thiazolidinediones Eicosanoids |
| gptkbp:locatedOnChromosome |
3p25.2
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
Mouse Pparg
Rat Pparg |
| gptkbp:pathway |
Adipogenesis
PPAR signaling pathway |
| gptkbp:postTranslationalModification |
Phosphorylation
Ubiquitination Sumoylation |
| gptkbp:protein_name |
gptkb:Peroxisome_proliferator-activated_receptor_gamma
|
| gptkbp:refersTo |
Human protein: Peroxisome proliferator-activated receptor gamma (PPARG)
|
| gptkbp:sequence |
505
|
| gptkbp:status |
Reviewed
|
| gptkbp:structure |
Contains a DNA-binding domain
Contains a ligand-binding domain |
| gptkbp:bfsParent |
gptkb:DUSP1
|
| gptkbp:bfsLayer |
7
|