| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:medical_condition
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:affects
                                    
                                 | 
                                
                                    
                                        
                                            
                                            glucose metabolism
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:associatedWith
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:polycystic_ovary_syndrome
                                        
                                         
                                    
                                        
                                            gptkb:type_2_diabetes
                                        
                                         
                                    
                                        
                                            gptkb:metabolic_syndrome
                                        
                                         
                                    
                                        
                                            
                                            obesity
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:canBeExacerbatedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            sedentary lifestyle
                                        
                                        
                                         
                                    
                                        
                                            
                                            sleep deprivation
                                        
                                        
                                         
                                    
                                        
                                            
                                            high sugar intake
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:canBeReversedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            lifestyle modification
                                        
                                        
                                         
                                    
                                        
                                            
                                            bariatric surgery
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:cause
                                    
                                 | 
                                
                                    
                                        
                                            
                                            genetic factors
                                        
                                        
                                         
                                    
                                        
                                            
                                            physical inactivity
                                        
                                        
                                         
                                    
                                        
                                            
                                            hyperglycemia
                                        
                                        
                                         
                                    
                                        
                                            
                                            chronic stress
                                        
                                        
                                         
                                    
                                        
                                            
                                            hyperinsulinemia
                                        
                                        
                                         
                                    
                                        
                                            
                                            high-fat diet
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:diagnosedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:oral_glucose_tolerance_test
                                        
                                         
                                    
                                        
                                            
                                            fasting insulin test
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:firstDescribed
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Wilhelm_Falta
                                        
                                         
                                    
                                        
                                            
                                            1929
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:improves
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:exercise
                                        
                                         
                                    
                                        
                                            
                                            weight loss
                                        
                                        
                                         
                                    
                                        
                                            
                                            dietary changes
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:involves
                                    
                                 | 
                                
                                    
                                        
                                            
                                            impaired insulin signaling
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:measures
                                    
                                 | 
                                
                                    
                                        
                                            
                                            glucose tolerance test
                                        
                                        
                                         
                                    
                                        
                                            
                                            HOMA-IR
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:occurredIn
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Cushing's_syndrome
                                        
                                         
                                    
                                        
                                            
                                            pregnancy
                                        
                                        
                                         
                                    
                                        
                                            
                                            acromegaly
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:prevalence
                                    
                                 | 
                                
                                    
                                        
                                            
                                            adults
                                        
                                        
                                         
                                    
                                        
                                            
                                            children
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:relatedTo
                                    
                                 | 
                                
                                    
                                        
                                            
                                            insulin sensitivity
                                        
                                        
                                         
                                    
                                        
                                            
                                            beta cell dysfunction
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:riskFactor
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:cardiovascular_disease
                                        
                                         
                                    
                                        
                                            gptkb:nonalcoholic_fatty_liver_disease
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:treatment
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:metformin
                                        
                                         
                                    
                                        
                                            gptkb:thiazolidinediones
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:P48736
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            7
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Insulin resistance
                                        
                                        
                                         
                                    
                                 |