P20701 (CD11a)

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:ITGAL
Integrin alpha-L
gptkbp:associatedWith gptkb:leukocyte_adhesion_deficiency
gptkbp:component integral component of plasma membrane
LFA-1 (lymphocyte function-associated antigen 1)
gptkbp:discoveredBy 1986
gptkbp:expressedIn gptkb:leukocytes
gptkbp:formsComplexWith CD18 (ITGB2)
gptkbp:function immune response
cell adhesion
leukocyte migration
cell adhesion molecule binding
gptkbp:gene ITGAL gene
gptkbp:GOProcess immune system process
https://www.w3.org/2000/01/rdf-schema#label P20701 (CD11a)
gptkbp:interactsWith gptkb:ICAM-1
gptkb:ICAM-2
gptkb:ICAM-3
gptkbp:locatedOnChromosome 16q13
gptkbp:location gptkb:cell_membrane
gptkbp:molecularWeight 128 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 1ZON
gptkbp:postTranslationalModification glycosylation
disulfide bond
gptkbp:sequence 1173 amino acids
gptkbp:subunit integrin alpha-L/beta-2 complex
gptkbp:UniProtID P20701
gptkbp:bfsParent gptkb:LFA-1
gptkbp:bfsLayer 8