|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:ER-alpha
gptkb:NR3A1
|
|
gptkbp:biologicalProcess
|
regulation of transcription
transcription factor activity
DNA-binding
estrogen signaling pathway
|
|
gptkbp:domain
|
zinc finger DNA-binding domain
nuclear hormone receptor ligand-binding domain
|
|
gptkbp:EC_number
|
2.3.1.-
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000091831
|
|
gptkbp:expressedIn
|
gptkb:bone
gptkb:prostate
gptkb:testis
brain
uterus
breast tissue
|
|
gptkbp:gene
|
gptkb:ESR1
|
|
gptkbp:hasCellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:hasDrugBankTargetID
|
BE0000337
|
|
gptkbp:hasGeneCardsID
|
gptkb:ESR1
|
|
gptkbp:hasIsoform
|
P04114-1
P04114-2
P04114-3
|
|
gptkbp:hasPharmGKBID
|
PA27338
|
|
gptkbp:hasRefSeqID
|
NP_000116.2
|
|
gptkbp:hasSequenceLength
|
595
|
|
gptkbp:HGNC_ID
|
3467
|
|
gptkbp:isAssociatedWithDisease
|
gptkb:cancer
gptkb:bone
gptkb:endometrial_cancer
|
|
gptkbp:KEGGID
|
hsa:2099
|
|
gptkbp:locatedOnChromosome
|
6q25.1
|
|
gptkbp:OMIM
|
133430
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1A52
1QKU
3ERT
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:Reactome
|
R-HSA-8939211
|
|
gptkbp:target
|
gptkb:fulvestrant
gptkb:tamoxifen
raloxifene
|
|
gptkbp:UniProt_entry_name
|
gptkb:Estrogen_receptor
|
|
gptkbp:UniProtID
|
gptkb:P04114
|
|
gptkbp:bfsParent
|
gptkb:apolipoprotein_B-100
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P04114
|