|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Beta-globin
gptkb:Hemoglobin_beta_chain
HBB_HUMAN
|
|
gptkbp:associatedWith
|
Beta-thalassemia
Sickle cell anemia
|
|
gptkbp:biologicalProcess
|
oxygen transport
oxygen binding
|
|
gptkbp:cellularComponent
|
gptkb:hemoglobin_complex
|
|
gptkbp:domain
|
Globin domain
|
|
gptkbp:EC_number
|
-
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000335295
|
|
gptkbp:expressedIn
|
erythrocyte
|
|
gptkbp:function
|
Oxygen transport
|
|
gptkbp:gene
|
gptkb:HBB
|
|
gptkbp:has_mutation
|
gptkb:E6V_(sickle_cell_mutation)
|
|
gptkbp:HGNC_ID
|
4827
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P02088
|
|
gptkbp:InterPro
|
IPR000971
|
|
gptkbp:is_reviewed
|
true
|
|
gptkbp:KEGGID
|
gptkb:hsa:3043
|
|
gptkbp:locatedOnChromosome
|
11
chr11:5225466-5227000 (GRCh38)
|
|
gptkbp:location
|
11p15.4
|
|
gptkbp:molecularWeight
|
15867 Da
|
|
gptkbp:mutationAssociatedWith
|
gptkb:beta-thalassemia
sickle cell disease
|
|
gptkbp:name
|
gptkb:Hemoglobin_subunit_beta
|
|
gptkbp:OMIM
|
141900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Hbb-b1
rat Hbb
chimpanzee HBB
|
|
gptkbp:partOf
|
adult hemoglobin (HbA)
fetal hemoglobin (HbF, minor component)
|
|
gptkbp:PDB
|
gptkb:4HHB
1A3N
2H35
|
|
gptkbp:proteinFamily
|
PF00042
|
|
gptkbp:Reactome
|
R-HSA-1247673
|
|
gptkbp:RefSeq
|
gptkb:NP_000509.1
|
|
gptkbp:sequence
|
147
|
|
gptkbp:STRING
|
9606.ENSP00000335295
|
|
gptkbp:structure
|
Globin fold
|
|
gptkbp:subunit
|
Hemoglobin
|
|
gptkbp:UniGene
|
Hs.654653
|
|
gptkbp:UniProt_entry_name
|
HBB_HUMAN
|
|
gptkbp:UniProt_release
|
2024_02
|
|
gptkbp:UniProtID
|
gptkb:P02088
|
|
gptkbp:bfsParent
|
gptkb:hbb-b1
|
|
gptkbp:bfsLayer
|
7
|