|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Ig_gamma-1_chain_C_region
IgG1 heavy chain constant region
IGH-1
Immunoglobulin G1 heavy chain
Immunoglobulin heavy chain gamma 1
|
|
gptkbp:biologicalProcess
|
immune response
antigen binding
|
|
gptkbp:component
|
gptkb:IgG1_antibody
|
|
gptkbp:disulfideBond
|
yes
|
|
gptkbp:EC_number
|
none
|
|
gptkbp:Entrez_Gene_ID
|
3500
ENSG00000211896
|
|
gptkbp:gene
|
gptkb:IGHG1
|
|
gptkbp:glycosylation
|
yes
|
|
gptkbp:has3DStructure
|
yes
|
|
gptkbp:hasChromosomeLocation
|
14q32.33
|
|
gptkbp:hasDisorderAssociation
|
leukemia
multiple myeloma
autoimmune diseases
immunodeficiency
monoclonal gammopathy
|
|
gptkbp:hasIsoform
|
1
|
|
gptkbp:hasPfamDomain
|
PF00047
|
|
gptkbp:hasRefSeqID
|
NP_001007
|
|
gptkbp:hasSequenceLength
|
330
|
|
gptkbp:hasTissueSpecificity
|
plasma cells
|
|
gptkbp:hasUniProtEntryName
|
IGHG1_HUMAN
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01850
|
|
gptkbp:InterPro
|
IPR003599
IPR007110
IPR013151
IPR036179
|
|
gptkbp:isAllergen
|
no
|
|
gptkbp:isAntibodyComponent
|
yes
|
|
gptkbp:isReviewedInUniProt
|
yes
|
|
gptkbp:mass
|
36.1 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:adaptive_immune_system
complement activation
Fc gamma receptor-mediated phagocytosis
|
|
gptkbp:postTranslationalModification
|
cleavage
glycosylation
disulfide bond
|
|
gptkbp:referencedIn
|
Ensembl:ENSG00000211896
NCBI Gene:3500
UniProt:P01850
|
|
gptkbp:signalPeptide
|
yes
|
|
gptkbp:significance
|
therapeutic antibody target
|
|
gptkbp:subcellularLocation
|
secreted
|
|
gptkbp:UniProt_entry_name
|
gptkb:Immunoglobulin_heavy_constant_gamma_1
|
|
gptkbp:UniProtID
|
gptkb:P01850
|
|
gptkbp:bfsParent
|
gptkb:TCRB_gene
gptkb:T-cell_receptor_beta_chain
gptkb:TRBC1
gptkb:TCRB
|
|
gptkbp:bfsLayer
|
8
|