Immunoglobulin heavy constant gamma 1

URI: https://gptkb.org/entity/Immunoglobulin_heavy_constant_gamma_1
GPTKB entity
Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Ig_gamma-1_chain_C_region
IgG1 heavy chain constant region
gptkbp:associatedWith gptkb:autoimmune_disease
gptkb:immunodeficiency
gptkbp:biologicalProcess antigen binding
immunoglobulin receptor binding
gptkbp:component gptkb:IgG1_antibody
gptkbp:Entrez_Gene_ID 3500
gptkbp:expressedIn gptkb:B_cells
gptkbp:foundIn humans
gptkbp:function mediates immune response
gptkbp:gene gptkb:IGHG1
gptkbp:involves humoral immune response
gptkbp:locatedOnChromosome 14
14q32.33
gptkbp:OMIM 147100
gptkbp:part_of immunoglobulin heavy chain
gptkbp:postTranslationalModification glycosylation
gptkbp:sequence 330 amino acids
gptkbp:significance used in therapeutic monoclonal antibodies
gptkbp:species gptkb:Homo_sapiens
gptkbp:structure composed of constant domains CH1, CH2, CH3
gptkbp:UniProtID P01857
gptkbp:bfsParent gptkb:UniProt:_P01889
gptkb:P01877
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label Immunoglobulin heavy constant gamma 1