Immunoglobulin heavy constant gamma 1
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Ig_gamma-1_chain_C_region
IgG1 heavy chain constant region |
| gptkbp:associatedWith |
immunodeficiency
autoimmune disease |
| gptkbp:biologicalProcess |
antigen binding
immunoglobulin receptor binding |
| gptkbp:component |
gptkb:IgG1_antibody
|
| gptkbp:Entrez_Gene_ID |
3500
|
| gptkbp:expressedIn |
gptkb:B_cells
|
| gptkbp:foundIn |
humans
|
| gptkbp:function |
mediates immune response
|
| gptkbp:gene |
gptkb:IGHG1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Immunoglobulin heavy constant gamma 1
|
| gptkbp:involves |
humoral immune response
|
| gptkbp:locatedOnChromosome |
14
14q32.33 |
| gptkbp:OMIM |
147100
|
| gptkbp:part_of |
immunoglobulin heavy chain
|
| gptkbp:postTranslationalModification |
glycosylation
|
| gptkbp:sequence |
330 amino acids
|
| gptkbp:significance |
used in therapeutic monoclonal antibodies
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
composed of constant domains CH1, CH2, CH3
|
| gptkbp:UniProtID |
P01857
|
| gptkbp:bfsParent |
gptkb:UniProt:P01848
|
| gptkbp:bfsLayer |
7
|