TCRB gene

URI: https://gptkb.org/entity/TCRB_gene
GPTKB entity
Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeSplicing yes
gptkbp:component gptkb:T-cell_receptor_complex
gptkbp:discoveredIn 1980s
gptkbp:encodes gptkb:T-cell_receptor_beta_chain
gptkbp:Entrez_Gene_ID 28645
gptkbp:expressedIn T lymphocytes
gptkbp:fullName gptkb:T_cell_receptor_beta_locus
gptkbp:function encodes the beta chain of the T-cell receptor complex
gptkbp:hasCSegment gptkb:TRBC
gptkbp:hasDSegment gptkb:TRBD
gptkbp:hasJSegment gptkb:TRBJ
gptkbp:hasVSegment gptkb:TRBV
gptkbp:HGNC_ID gptkb:HGNC:12154
https://www.w3.org/2000/01/rdf-schema#label TCRB gene
gptkbp:involvedIn adaptive immune response
gptkbp:locatedOnChromosome gptkb:7q34
gptkb:chromosome_7
gptkbp:mutationAssociatedWith gptkb:T-cell_leukemia
immunodeficiency
gptkbp:numberOfExons variable (due to V, D, J, and C segments)
gptkbp:OMIM 186930
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Trb
gptkbp:relatedTo gptkb:TCRD_gene
gptkb:TCRG_gene
gptkb:TCRA_gene
gptkbp:UniProtID gptkb:P01850
gptkbp:bfsParent gptkb:alpha-beta_TCR
gptkbp:bfsLayer 7