|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:IRDN
preproinsulin
proinsulin
ILPR
|
|
gptkbp:associatedWith
|
gptkb:diabetes_mellitus
|
|
gptkbp:biologicalProcess
|
carbohydrate metabolic process
hormone activity
insulin receptor signaling pathway
|
|
gptkbp:containsGene
|
gptkb:INS
|
|
gptkbp:disulfideBond
|
A20-B19
A7-B7
A6-A11
|
|
gptkbp:EC_number
|
none
|
|
gptkbp:Entrez_Gene_ID
|
3630
|
|
gptkbp:function
|
regulation of glucose homeostasis
|
|
gptkbp:GO
|
gptkb:GO:0006006
GO:0005179
GO:0032868
|
|
gptkbp:hasChainA
|
25-54
|
|
gptkbp:hasChainB
|
90-110
|
|
gptkbp:hasChEMBL
|
CHEMBL1201576
|
|
gptkbp:hasDrugBank
|
DB00030
|
|
gptkbp:hasEnsembl
|
ENSP00000250971
|
|
gptkbp:hasHGNC
|
HGNC:6081
|
|
gptkbp:hasPfam
|
gptkb:PF00049
|
|
gptkbp:hasReactome
|
gptkb:R-HSA-264876
|
|
gptkbp:hasRefSeqID
|
gptkb:NP_000198.1
|
|
gptkbp:hasUniGene
|
gptkb:Hs.654592
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P00558
|
|
gptkbp:InterPro
|
gptkb:IPR022352
|
|
gptkbp:isAllergen
|
false
|
|
gptkbp:KEGGID
|
gptkb:hsa:3630
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
11
|
|
gptkbp:mass
|
11793 Da
|
|
gptkbp:name
|
gptkb:Insulin
|
|
gptkbp:OMIM
|
176730
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
9606
|
|
gptkbp:PDB
|
gptkb:2MVC
1ZNJ
4EY1
|
|
gptkbp:reviewedBy
|
true
|
|
gptkbp:sequence
|
110
|
|
gptkbp:signalPeptide
|
1-24
|
|
gptkbp:structure
|
heterodimer of A and B chains linked by disulfide bonds
|
|
gptkbp:subcellularLocation
|
secreted
|
|
gptkbp:UniProtID
|
gptkb:P00558
|
|
gptkbp:bfsParent
|
gptkb:PGK1
|
|
gptkbp:bfsLayer
|
8
|