|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:Diabetes_mellitus
|
|
gptkbp:disulfideBond
|
Between A and B chains
|
|
gptkbp:EC_number
|
nan
|
|
gptkbp:Entrez_Gene_ID
|
3630
ENSP00000250971
|
|
gptkbp:enzymeRegulation
|
Binds to insulin receptor
|
|
gptkbp:function
|
Regulation of glucose homeostasis
|
|
gptkbp:hasGeneCardsID
|
gptkb:INS
|
|
gptkbp:hasGeneName
|
gptkb:INS
|
|
gptkbp:hasGOAnnotation
|
gptkb:GO:0006006
GO:0005158
GO:0005520
|
|
gptkbp:hasPfam
|
gptkb:PF00049
|
|
gptkbp:hasPharmGKBID
|
PA164712498
|
|
gptkbp:hasProteinExistence
|
Evidence at protein level
|
|
gptkbp:hasRefSeqID
|
gptkb:NP_000198.1
|
|
gptkbp:hasTaxonomyID
|
9606
|
|
gptkbp:hasUniGeneID
|
Hs.654508
|
|
gptkbp:HGNC_ID
|
HGNC:6081
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P00257
|
|
gptkbp:InterPro
|
gptkb:IPR022352
IPR016179
|
|
gptkbp:isAllergen
|
No
|
|
gptkbp:isHormone
|
Yes
|
|
gptkbp:KEGGID
|
gptkb:hsa:3630
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
11
|
|
gptkbp:molecularWeight
|
11793 Da
|
|
gptkbp:OMIM
|
176730
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1TRZ
gptkb:2HIU
gptkb:4EWW
|
|
gptkbp:postTranslationalModification
|
C-peptide cleavage
|
|
gptkbp:products
|
gptkb:Proinsulin
|
|
gptkbp:protein_name
|
gptkb:Insulin
|
|
gptkbp:PubChem_CID
|
DB00030
CHEMBL1201576
|
|
gptkbp:Reactome
|
gptkb:R-HSA-264876
R-HSA-74713
R-HSA-74751
|
|
gptkbp:sequence
|
110
|
|
gptkbp:sequenceStatus
|
Mature protein
|
|
gptkbp:signalPeptide
|
Present
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:targetOfDrug
|
Yes
|
|
gptkbp:UniProtID
|
gptkb:P00257
|
|
gptkbp:bfsParent
|
gptkb:Ferredoxin
|
|
gptkbp:bfsLayer
|
7
|