Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Protein precursor
|
| gptkbp:cleavage |
Carboxypeptidase E
Prohormone convertases |
| gptkbp:contains |
gptkb:C-peptide
A chain B chain |
| gptkbp:discoveredBy |
gptkb:Donald_F._Steiner
|
| gptkbp:discoveredIn |
1967
|
| gptkbp:encodedBy |
gptkb:INS_gene
|
| gptkbp:foundIn |
gptkb:Pancreatic_beta_cells
|
| gptkbp:function |
Precursor to active insulin
|
| gptkbp:hasAminoAcidSequence |
110 amino acids (human)
|
| https://www.w3.org/2000/01/rdf-schema#label |
Proinsulin
|
| gptkbp:location |
Secretory granules of beta cells
|
| gptkbp:measures |
Blood tests for diabetes diagnosis
|
| gptkbp:molecularWeight |
~9 kDa
|
| gptkbp:predecessor |
gptkb:C-peptide
gptkb:Insulin |
| gptkbp:relatedTo |
gptkb:Diabetes_mellitus
|
| gptkbp:structure |
Single polypeptide chain
|
| gptkbp:UniProtID |
P01308
|
| gptkbp:bfsParent |
gptkb:P04049
gptkb:P21136 |
| gptkbp:bfsLayer |
7
|