Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antiretroviral drug class
|
| gptkbp:administeredBy |
oral route
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:category |
antiviral drugs
nucleoside analogues |
| gptkbp:discoveredIn |
late 1980s
|
| gptkbp:drugClass |
gptkb:tenofovir_disoproxil_fumarate
gptkb:didanosine gptkb:stavudine gptkb:zalcitabine gptkb:abacavir gptkb:lamivudine gptkb:zidovudine emtricitabine |
| https://www.w3.org/2000/01/rdf-schema#label |
NRTIs
|
| gptkbp:mechanismOfAction |
block viral DNA synthesis
inhibit reverse transcriptase |
| gptkbp:notEffectiveAgainst |
gptkb:HIV_integrase
HIV protease |
| gptkbp:sideEffect |
gptkb:anemia
peripheral neuropathy lactic acidosis hepatic steatosis |
| gptkbp:standsFor |
gptkb:Nucleoside_Reverse_Transcriptase_Inhibitors
|
| gptkbp:target |
gptkb:HIV-1
gptkb:HIV-2 |
| gptkbp:used_in |
combination drug
|
| gptkbp:usedFor |
HIV treatment
|
| gptkbp:bfsParent |
gptkb:HIV/AIDS
|
| gptkbp:bfsLayer |
4
|