|
gptkbp:instanceOf
|
antiviral drug
protease inhibitor
|
|
gptkbp:approvedBy
|
gptkb:FDA
1991
|
|
gptkbp:ATCCode
|
J05AF02
|
|
gptkbp:brand
|
gptkb:Videx
gptkb:Videx_EC
|
|
gptkbp:CASNumber
|
69655-05-6
|
|
gptkbp:category
|
gptkb:WHO_essential_medicine
antiviral drug
antiretroviral therapy
purine analogue
organonitrogen compound
organoxygen compound
|
|
gptkbp:chemicalClass
|
purine analogue
|
|
gptkbp:contraindication
|
alcohol abuse
history of pancreatitis
|
|
gptkbp:discoveredBy
|
gptkb:Merck_&_Co.
|
|
gptkbp:drugInteraction
|
gptkb:stavudine
ribavirin
allopurinol
tenofovir
|
|
gptkbp:eliminationHalfLife
|
1.5 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C10H12N4O3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
didanosine
|
|
gptkbp:IUPACName
|
gptkb:9-(2,3-dihydroxypropyl)adenine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits reverse transcriptase
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
236.23 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
135398508
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
diarrhea
abdominal pain
pancreatitis
peripheral neuropathy
hepatomegaly
lactic acidosis
|
|
gptkbp:UNII
|
Q60PKS4ET8
|
|
gptkbp:usedFor
|
HIV infection
|
|
gptkbp:bfsParent
|
gptkb:NRTIs
|
|
gptkbp:bfsLayer
|
5
|