|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:activatedBy
|
oxysterols
|
|
gptkbp:alias
|
gptkb:LXR-beta
gptkb:LXRb
gptkb:Nuclear_receptor_subfamily_1_group_H_member_2
|
|
gptkbp:associatedWith
|
atherosclerosis
lipid metabolism
|
|
gptkbp:discoveredBy
|
1995
|
|
gptkbp:encodes
|
gptkb:Liver_X_receptor_beta
|
|
gptkbp:Entrez_Gene_ID
|
7376
ENSG00000174417
|
|
gptkbp:expressedIn
|
brain
liver
adipose tissue
macrophages
|
|
gptkbp:function
|
regulation of cholesterol, fatty acid, and glucose homeostasis
|
|
gptkbp:geneType
|
protein coding
|
|
gptkbp:has_clinical_relevance
|
gptkb:metabolic_syndrome
neurodegenerative diseases
inflammation
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
7962
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NR1H2
|
|
gptkbp:inhibitedBy
|
inverse agonists
|
|
gptkbp:interactsWith
|
gptkb:RXR_(Retinoid_X_Receptor)
|
|
gptkbp:length
|
460
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
19q13.33
|
|
gptkbp:molecularWeight
|
50
|
|
gptkbp:OMIM
|
602423
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Nr1h2
|
|
gptkbp:proteinFamily
|
DNA-binding domain
ligand-binding domain
nuclear receptor family
|
|
gptkbp:reference_protein_(RefSeq)
|
gptkb:NP_009052
|
|
gptkbp:reference_sequence_(RefSeq)
|
gptkb:NM_007121
|
|
gptkbp:regulates
|
gptkb:ABCA1
gptkb:CYP7A1
gptkb:SREBP-1c
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:transcription_factor
|
yes
|
|
gptkbp:UniProtID
|
P55055
|
|
gptkbp:bfsParent
|
gptkb:LXR
|
|
gptkbp:bfsLayer
|
6
|