|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activeSiteResidue
|
Cys152
His179
|
|
gptkbp:alternativeName
|
gptkb:EC_1.2.1.12
gptkb:Peptidyl-cysteine_S-nitrosylase_GAPDH
gptkb:GAPDH
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
|
|
gptkbp:cofactor
|
NAD+
|
|
gptkbp:disulfideBond
|
Cys152-Cys156
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000374867
2597
|
|
gptkbp:enzymeCommissionNumber
|
1.2.1.12
|
|
gptkbp:expressedIn
|
housekeeping gene
|
|
gptkbp:function
|
catalyzes the sixth step of glycolysis
|
|
gptkbp:gene
|
gptkb:GAPDH
|
|
gptkbp:GO_term
|
gptkb:GO:0006006
GO:0005737
GO:0006096
|
|
gptkbp:hasIsoform
|
2
|
|
gptkbp:HGNC_ID
|
4141
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P04424
|
|
gptkbp:length
|
335
|
|
gptkbp:locatedOnChromosome
|
gptkb:12p13.31
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
36000
|
|
gptkbp:OMIM
|
138400
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:yeast_TDH1
mouse GAPDH
rat GAPDH
|
|
gptkbp:pathway
|
glycolysis
gluconeogenesis
|
|
gptkbp:PDB
|
gptkb:1ZNQ
gptkb:2V4O
1U8F
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
S-nitrosylation
|
|
gptkbp:protein_name
|
gptkb:Glyceraldehyde-3-phosphate_dehydrogenase
|
|
gptkbp:reference_sequence_(RefSeq)
|
gptkb:NP_002037.2
|
|
gptkbp:sequenceStatus
|
reviewed
|
|
gptkbp:sequenceVersion
|
4
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
gptkb:nucleus
cytosol
mitochondrion
|
|
gptkbp:subunit
|
homotetramer
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
gptkb:P04424
|
|
gptkbp:bfsParent
|
gptkb:argininosuccinate_lyase
|
|
gptkbp:bfsLayer
|
6
|