|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:activatedBy
|
inflammatory cytokine production
|
|
gptkbp:alsoKnownAs
|
CARD15
|
|
gptkbp:discoveredBy
|
Hugot et al.
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodes
|
NOD2 protein
|
|
gptkbp:Entrez_Gene_ID
|
64127
ENSG00000167207
|
|
gptkbp:expressedIn
|
dendritic cells
macrophages
monocytes
|
|
gptkbp:fullName
|
nucleotide-binding oligomerization domain-containing protein 2
|
|
gptkbp:function
|
innate immune response
recognition of bacterial peptidoglycan
|
|
gptkbp:HGNC_ID
|
HGNC:5331
|
|
gptkbp:interactsWith
|
gptkb:RIPK2
ATG16L1
|
|
gptkbp:ligand
|
muramyl dipeptide
|
|
gptkbp:locatedOnChromosome
|
16q12
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Crohn's_disease
gptkb:Blau_syndrome
Yao syndrome
|
|
gptkbp:OMIM
|
605956
|
|
gptkbp:orthologInMouse
|
Nod2
|
|
gptkbp:proteinFamily
|
gptkb:CARD_domain
NACHT domain
leucine-rich repeat (LRR) domain
|
|
gptkbp:regulates
|
gptkb:NF-kappaB_signaling_pathway
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
Q9HC29
|
|
gptkbp:bfsParent
|
gptkb:chromosome_16
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NOD2
|