Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:GAP
|
| gptkbp:binds |
guanine nucleotide exchange factor
|
| gptkbp:category |
enzyme regulator
|
| gptkbp:example |
gptkb:ArfGAP
gptkb:RasGAP gptkb:RhoGAP |
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
stimulates GTPase activity of G proteins
|
| https://www.w3.org/2000/01/rdf-schema#label |
GTPase-activating protein
|
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:mechanismOfAction |
increases hydrolysis of GTP to GDP
|
| gptkbp:mutationAssociatedWith |
can lead to cancer
|
| gptkbp:opposedBy |
guanine nucleotide exchange factors
|
| gptkbp:regulates |
GTP-binding proteins
|
| gptkbp:role |
vesicle trafficking
cell signaling cytoskeleton organization cell growth regulation |
| gptkbp:bfsParent |
gptkb:GAP-1_protein
gptkb:RalBP1 gptkb:RASA3 gptkb:NF1_protein gptkb:neurofibromin |
| gptkbp:bfsLayer |
7
|