Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
Sprouty-related, EVH1 domain-containing protein 1
SPRED-1 |
| gptkbp:associatedWith |
gptkb:Legius_syndrome
|
| gptkbp:discoveredIn |
2002
|
| gptkbp:domain |
gptkb:EVH1_domain
gptkb:SPR_domain c-Kit binding domain |
| gptkbp:encodes |
Sprouty-related EVH1 domain-containing protein 1
|
| gptkbp:Entrez_Gene_ID |
161742
ENSG00000165388 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:HGNC_ID |
HGNC:15541
|
| https://www.w3.org/2000/01/rdf-schema#label |
SPRED1
|
| gptkbp:inhibitedBy |
Ras/MAPK pathway
|
| gptkbp:interactsWith |
gptkb:Raf1
gptkb:c-Kit neurofibromin (NF1) |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_15
15q14 |
| gptkbp:mutationAssociatedWith |
gptkb:Legius_syndrome
loss-of-function |
| gptkbp:OMIM |
609291
|
| gptkbp:orthologInMouse |
Spred1
|
| gptkbp:proteinFamily |
gptkb:SPRED_family
|
| gptkbp:regulates |
gptkb:MAPK/ERK_signaling_pathway
|
| gptkbp:UniProtID |
Q7Z699
|
| gptkbp:bfsParent |
gptkb:NF1_protein
|
| gptkbp:bfsLayer |
7
|