NDM-type metallo-beta-lactamases
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:NDM
gptkb:New_Delhi_metallo-beta-lactamase |
| gptkbp:class |
Ambler class B beta-lactamase
|
| gptkbp:cofactor |
zinc
|
| gptkbp:discoveredBy |
gptkb:New_Delhi,_India
gptkb:Klebsiella_pneumoniae |
| gptkbp:discoveredIn |
2008
|
| gptkbp:encodedBy |
blaNDM gene
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa gptkb:Acinetobacter_baumannii |
| https://www.w3.org/2000/01/rdf-schema#label |
NDM-type metallo-beta-lactamases
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:sulbactam gptkb:EDTA tazobactam |
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:publicHealthConcern |
antibiotic resistance
|
| gptkbp:resistantTo |
carbapenem antibiotics
|
| gptkbp:spreadTo |
plasmids
|
| gptkbp:subclassOf |
metallo-beta-lactamase
|
| gptkbp:threats |
critical
|
| gptkbp:variant |
gptkb:NDM-1
gptkb:NDM-2 gptkb:NDM-5 gptkb:NDM-7 gptkb:NDM-9 |
| gptkbp:bfsParent |
gptkb:IMP-I
|
| gptkbp:bfsLayer |
7
|