NCOA4

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alias DKFZp686A13122
ARA70
FLJ20421
prostate androgen-regulated protein
gptkbp:associatedWith gptkb:papillary_thyroid_carcinoma
prostate cancer
gptkbp:discoveredBy 1997
gptkbp:Entrez_Gene_ID 8031
ENSG00000124151
gptkbp:expressedIn gptkb:thyroid
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:testis
brain
heart
liver
pancreas
gptkbp:fullName Nuclear receptor coactivator 4
gptkbp:function acts as a coactivator for nuclear hormone receptors
involved in ferritinophagy
gptkbp:geneType protein-coding
gptkbp:GO_term GO:0003700 (DNA-binding transcription factor activity)
GO:0005634 (nucleus)
GO:0005515 (protein binding)
gptkbp:HGNC_ID gptkb:NCOA4
https://www.w3.org/2000/01/rdf-schema#label NCOA4
gptkbp:interactsWith gptkb:androgen_receptor
estrogen receptor alpha
nuclear hormone receptors
gptkbp:length 614
gptkbp:locatedOnChromosome 10q11.2
gptkbp:molecularWeight ~70 kDa
gptkbp:mutationAssociatedWith gene fusion with RET in papillary thyroid carcinoma
gptkbp:OMIM 601566
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:mouse
gptkb:zebrafish
right
gptkbp:reference_sequence_protein NP_005111
gptkbp:RefSeq NM_005120
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID Q13772
gptkbp:bfsParent gptkb:RET_fusion-positive_thyroid_cancer
gptkbp:bfsLayer 7