Statements (55)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:cancer
|
gptkbp:complication |
distant metastasis
hypoparathyroidism (post-surgery) local recurrence recurrent laryngeal nerve injury (post-surgery) |
gptkbp:firstDescribed |
gptkb:Malassez
1880 |
gptkbp:has5YearSurvivalRate |
>95%
|
gptkbp:hasDiagnosticMethod |
ultrasound
histopathology fine needle aspiration biopsy |
gptkbp:hasEpidemiology |
more common in women
increasing incidence worldwide |
gptkbp:hasGeneticAlteration |
gptkb:RET/PTC_rearrangement
BRAF mutation |
gptkbp:hasHistologicalFeature |
Orphan Annie eye nuclei
nuclear grooves psammoma bodies |
gptkbp:hasMetastasisSite |
lungs
lymph nodes bones |
gptkbp:hasTypicalAgeOfOnset |
30-50 years
|
https://www.w3.org/2000/01/rdf-schema#label |
papillary thyroid carcinoma
|
gptkbp:ICD-10_code |
gptkb:C73
|
gptkbp:prevalence |
accounts for about 80% of thyroid cancers
most common type of thyroid cancer |
gptkbp:prognosis |
age
lymph node involvement generally excellent tumor size distant metastasis extrathyroidal extension |
gptkbp:recurrence |
5-20%
|
gptkbp:riskFactor |
family history
radiation exposure female sex |
gptkbp:stageName |
gptkb:TNM_staging
|
gptkbp:symptom |
hoarseness
dysphagia neck mass thyroid nodule |
gptkbp:synonym |
gptkb:PTC
papillary thyroid cancer papillary carcinoma of the thyroid |
gptkbp:treatment |
radioactive iodine therapy
thyroidectomy TSH suppression therapy external beam radiation (rare cases) |
gptkbp:bfsParent |
gptkb:diffuse_sclerosing_variant_papillary_thyroid_cancer
gptkb:follicular_variant_papillary_thyroid_cancer gptkb:tall_cell_variant_papillary_thyroid_cancer gptkb:7q34_(BRAF) gptkb:BRAF_V600E gptkb:RET/PTC_rearrangement |
gptkbp:bfsLayer |
6
|