Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cancer
|
| gptkbp:complication |
distant metastasis
hypoparathyroidism (post-surgery) local recurrence recurrent laryngeal nerve injury (post-surgery) |
| gptkbp:firstDescribed |
gptkb:Malassez
1880 |
| gptkbp:has5YearSurvivalRate |
>95%
|
| gptkbp:hasDiagnosticMethod |
ultrasound
histopathology fine needle aspiration biopsy |
| gptkbp:hasEpidemiology |
more common in women
increasing incidence worldwide |
| gptkbp:hasGeneticAlteration |
gptkb:RET/PTC_rearrangement
BRAF mutation |
| gptkbp:hasHistologicalFeature |
Orphan Annie eye nuclei
nuclear grooves psammoma bodies |
| gptkbp:hasMetastasisSite |
lungs
lymph nodes bones |
| gptkbp:hasTypicalAgeOfOnset |
30-50 years
|
| gptkbp:ICD-10_code |
gptkb:C73
|
| gptkbp:prevalence |
accounts for about 80% of thyroid cancers
most common type of thyroid cancer |
| gptkbp:prognosis |
age
lymph node involvement generally excellent tumor size distant metastasis extrathyroidal extension |
| gptkbp:recurrence |
5-20%
|
| gptkbp:riskFactor |
family history
radiation exposure female sex |
| gptkbp:stageName |
gptkb:TNM_staging
|
| gptkbp:symptom |
hoarseness
dysphagia neck mass thyroid nodule |
| gptkbp:synonym |
gptkb:PTC
papillary thyroid cancer papillary carcinoma of the thyroid |
| gptkbp:treatment |
radioactive iodine therapy
thyroidectomy TSH suppression therapy external beam radiation (rare cases) |
| gptkbp:bfsParent |
gptkb:7q34_(BRAF)
gptkb:BRAF_V600E |
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
papillary thyroid carcinoma
|