papillary thyroid carcinoma

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:complication distant metastasis
hypoparathyroidism (post-surgery)
local recurrence
recurrent laryngeal nerve injury (post-surgery)
gptkbp:firstDescribed gptkb:Malassez
1880
gptkbp:has5YearSurvivalRate >95%
gptkbp:hasDiagnosticMethod ultrasound
histopathology
fine needle aspiration biopsy
gptkbp:hasEpidemiology more common in women
increasing incidence worldwide
gptkbp:hasGeneticAlteration gptkb:RET/PTC_rearrangement
BRAF mutation
gptkbp:hasHistologicalFeature Orphan Annie eye nuclei
nuclear grooves
psammoma bodies
gptkbp:hasMetastasisSite lungs
lymph nodes
bones
gptkbp:hasTypicalAgeOfOnset 30-50 years
https://www.w3.org/2000/01/rdf-schema#label papillary thyroid carcinoma
gptkbp:ICD-10_code gptkb:C73
gptkbp:prevalence accounts for about 80% of thyroid cancers
most common type of thyroid cancer
gptkbp:prognosis age
lymph node involvement
generally excellent
tumor size
distant metastasis
extrathyroidal extension
gptkbp:recurrence 5-20%
gptkbp:riskFactor family history
radiation exposure
female sex
gptkbp:stageName gptkb:TNM_staging
gptkbp:symptom hoarseness
dysphagia
neck mass
thyroid nodule
gptkbp:synonym gptkb:PTC
papillary thyroid cancer
papillary carcinoma of the thyroid
gptkbp:treatment radioactive iodine therapy
thyroidectomy
TSH suppression therapy
external beam radiation (rare cases)
gptkbp:bfsParent gptkb:diffuse_sclerosing_variant_papillary_thyroid_cancer
gptkb:follicular_variant_papillary_thyroid_cancer
gptkb:tall_cell_variant_papillary_thyroid_cancer
gptkb:7q34_(BRAF)
gptkb:BRAF_V600E
gptkb:RET/PTC_rearrangement
gptkbp:bfsLayer 6