Mouse double minute 2 homolog
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:MDM2
|
| gptkbp:encodedBy |
MDM2 gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:E3_ubiquitin-protein_ligase
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mouse double minute 2 homolog
|
| gptkbp:inhibitedBy |
gptkb:p53
|
| gptkbp:interactsWith |
gptkb:ARF
gptkb:p53 ribosomal proteins |
| gptkbp:involvedIn |
apoptosis
cell cycle regulation DNA damage response |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
gptkb:12q15
|
| gptkbp:molecularWeight |
~55 kDa
|
| gptkbp:overexpressedIn |
various cancers
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:regulates |
p53 tumor suppressor
|
| gptkbp:bfsParent |
gptkb:Mdm2
|
| gptkbp:bfsLayer |
7
|