Metalloproteinase inhibitor 1
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:Tissue_inhibitor_of_metalloproteinases_1
gptkb:TIMP1 |
| gptkbp:encodedBy |
gptkb:TIMP1_gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000102265
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
inhibits matrix metalloproteinases
regulates extracellular matrix |
| gptkbp:gene |
gptkb:TIMP1
|
| gptkbp:HGNC_ID |
gptkb:HGNC:11820
|
| https://www.w3.org/2000/01/rdf-schema#label |
Metalloproteinase inhibitor 1
|
| gptkbp:involves |
apoptosis
cell proliferation angiogenesis tissue remodeling |
| gptkbp:locatedOnChromosome |
gptkb:X_chromosome
|
| gptkbp:molecularWeight |
28 kDa
|
| gptkbp:OMIM |
305370
|
| gptkbp:regulates |
matrix metalloproteinase activity
|
| gptkbp:significance |
biomarker for cancer
involved in cardiovascular disease involved in fibrosis |
| gptkbp:structure |
contains N-terminal and C-terminal domains
|
| gptkbp:UniProtID |
gptkb:P01033
|
| gptkbp:bfsParent |
gptkb:TIMP1
|
| gptkbp:bfsLayer |
7
|