Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
collectin |
| gptkbp:activatedBy |
gptkb:lectin_pathway
complement system |
| gptkbp:alternativeName |
gptkb:MBL2_protein
gptkb:mannan-binding_lectin gptkb:MBL |
| gptkbp:binds |
gptkb:N-acetylglucosamine
mannose residues |
| gptkbp:deficiencyCauses |
increased susceptibility to infections
|
| gptkbp:discoveredBy |
Kawasaki et al.
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:MBL2_gene
|
| gptkbp:foundIn |
gptkb:human
other mammals |
| gptkbp:function |
pattern recognition
innate immune system |
| https://www.w3.org/2000/01/rdf-schema#label |
Mannose-binding lectin
|
| gptkbp:interactsWith |
gptkb:MASP-1
gptkb:MASP-2 |
| gptkbp:location |
blood plasma
|
| gptkbp:medicalUse |
biomarker for immune deficiency
|
| gptkbp:relatedTo |
gptkb:complement_component_C2
gptkb:complement_component_C3 gptkb:complement_component_C4 |
| gptkbp:structure |
carbohydrate recognition domain
collagen-like domain oligomeric |
| gptkbp:bfsParent |
gptkb:MBL
|
| gptkbp:bfsLayer |
6
|