Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
complement system component |
| gptkbp:alternativeName |
C4
C4A C4B |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
autoimmune diseases |
| gptkbp:cleavage |
gptkb:C4b
C4a C4c C4d |
| gptkbp:deficiencyCauses |
increased susceptibility to infections
|
| gptkbp:encodedBy |
gptkb:C4A_gene
gptkb:C4B_gene |
| gptkbp:foundIn |
gptkb:human
other mammals |
| gptkbp:function |
immune response
activation of classical complement pathway activation of lectin complement pathway |
| https://www.w3.org/2000/01/rdf-schema#label |
complement component C4
|
| gptkbp:locatedOnChromosome |
gptkb:6p21.3
|
| gptkbp:location |
blood plasma
|
| gptkbp:molecularWeight |
~210 kDa (precursor)
|
| gptkbp:OMIM |
120810
|
| gptkbp:partOf |
complement cascade
|
| gptkbp:subunit |
C3/C5 convertase (classical pathway)
|
| gptkbp:UniProtID |
P0C0L4
P0C0L5 |
| gptkbp:bfsParent |
gptkb:Mannose-binding_lectin
|
| gptkbp:bfsLayer |
7
|