Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
C2
C2a fragment C2b fragment complement C2 |
| gptkbp:cleavage |
gptkb:C1s
|
| gptkbp:deficiencyAssociatedWith |
autoimmune diseases
|
| gptkbp:deficiencyCauses |
increased susceptibility to bacterial infections
|
| gptkbp:encodedBy |
C2 gene
|
| gptkbp:expressedIn |
liver
|
| gptkbp:form |
C3 convertase (C4b2a)
|
| gptkbp:formsComplexWith |
complement component C4b
|
| gptkbp:foundIn |
gptkb:human
other mammals |
| gptkbp:function |
gptkb:immune_response
cleavage to form C2a and C2b fragments |
| gptkbp:HGNC_ID |
HGNC:1323
|
| gptkbp:locatedOnChromosome |
gptkb:6p21.3
|
| gptkbp:molecularWeight |
102 kDa (precursor)
|
| gptkbp:OMIM |
217000
|
| gptkbp:partOf |
gptkb:lectin_pathway
classical complement pathway |
| gptkbp:presentIn |
blood plasma
|
| gptkbp:UniProtID |
P06681
|
| gptkbp:bfsParent |
gptkb:Mannose-binding_lectin
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
complement component C2
|