Statements (27)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
C2
C2a fragment C2b fragment complement C2 |
gptkbp:cleavage |
gptkb:C1s
|
gptkbp:deficiencyAssociatedWith |
autoimmune diseases
|
gptkbp:deficiencyCauses |
increased susceptibility to bacterial infections
|
gptkbp:encodedBy |
C2 gene
|
gptkbp:expressedIn |
liver
|
gptkbp:form |
C3 convertase (C4b2a)
|
gptkbp:formsComplexWith |
complement component C4b
|
gptkbp:foundIn |
gptkb:human
other mammals |
gptkbp:function |
immune response
cleavage to form C2a and C2b fragments |
gptkbp:HGNC_ID |
HGNC:1323
|
https://www.w3.org/2000/01/rdf-schema#label |
complement component C2
|
gptkbp:locatedOnChromosome |
gptkb:6p21.3
|
gptkbp:molecularWeight |
102 kDa (precursor)
|
gptkbp:OMIM |
217000
|
gptkbp:partOf |
gptkb:lectin_pathway
classical complement pathway |
gptkbp:presentIn |
blood plasma
|
gptkbp:UniProtID |
P06681
|
gptkbp:bfsParent |
gptkb:Mannose-binding_lectin
|
gptkbp:bfsLayer |
7
|