Multiple System Atrophy, Cerebellar type

URI: https://gptkb.org/entity/Multiple_System_Atrophy,_Cerebellar_type
GPTKB entity
Statements (43)
Predicate Object
gptkbp:instanceOf neurodegenerative disease
gptkbp:abbreviation gptkb:MSA-C
gptkbp:affects gptkb:basal_ganglia
gptkb:cerebellum
autonomic nervous system
gptkbp:associatedWith oligodendroglial cytoplasmic inclusions
gptkbp:cause unknown
gptkbp:characterizedBy autonomic dysfunction
parkinsonism
cerebellar ataxia
gptkbp:diagnosedBy clinical evaluation
MRI brain
gptkbp:differentialDiagnosis gptkb:Parkinson's_disease
gptkb:progressive_supranuclear_palsy
spinocerebellar ataxia
gptkbp:firstDescribed 1960s
gptkbp:gender slightly more common in men
gptkbp:hasEpidemiology rare
https://www.w3.org/2000/01/rdf-schema#label Multiple System Atrophy, Cerebellar type
gptkbp:ICD-10_code G23.2
gptkbp:medianSurvival 6-10 years
gptkbp:MeSH_ID D020754
gptkbp:MRI_finding hot cross bun sign
gptkbp:notableFeature lack of response to levodopa
gptkbp:OMIM 146500
gptkbp:onset adult
50-60 years
gptkbp:pathology alpha-synuclein accumulation
gptkbp:prevalence 3-5 per 100,000
gptkbp:prognosis poor
gptkbp:progression gptkb:fire
gptkbp:riskFactor unknown
gptkbp:subspecies gptkb:Multiple_System_Atrophy
gptkbp:symptom gptkb:orthostatic_hypotension
gait disturbance
dysphagia
urinary incontinence
dysarthria
gptkbp:treatment supportive care
physical therapy
medications for symptoms
gptkbp:bfsParent gptkb:MSA-C
gptkbp:bfsLayer 8