Trithorax-group (TrxG) protein family

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:amendedBy histones
gptkbp:associatedWith chromatin remodeling
gptkbp:catalyzes histone H3 lysine 4 methylation
gptkbp:contains SET domain proteins
chromatin remodeling factors
histone acetyltransferases
gptkbp:discoveredBy gptkb:Drosophila_melanogaster
gptkbp:enemyOf gptkb:Polycomb-group_(PcG)_protein_family
gptkbp:foundIn eukaryotes
gptkbp:function transcriptional activation
epigenetic regulation
https://www.w3.org/2000/01/rdf-schema#label Trithorax-group (TrxG) protein family
gptkbp:includes gptkb:BRM
gptkb:CBP
gptkb:ASH1
gptkb:MLL1
gptkbp:regulates gptkb:HOX_genes
developmental genes
gptkbp:role cell fate determination
stem cell maintenance
gene expression memory
gptkbp:bfsParent gptkb:Polycomb-group_(PcG)_protein_family
gptkbp:bfsLayer 7