Statements (78)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
gptkb:RNA_Polymerase |
| gptkbp:associated_with |
aging
tumor suppression |
| gptkbp:community |
immune response
|
| gptkbp:conservation |
many species
|
| gptkbp:downregulated_in |
various cancers
|
| gptkbp:has_family |
mi R-34 family
|
| gptkbp:has_function |
tumor suppressor activity
|
| gptkbp:has_role |
apoptosis
cell differentiation inflammation |
| gptkbp:has_variants |
MIR34 A
MIR34 B MIR34 C |
| https://www.w3.org/2000/01/rdf-schema#label |
MIR34
|
| gptkbp:influences |
DNA repair mechanisms
metastasis |
| gptkbp:initiated_by |
cell proliferation
|
| gptkbp:interacts_with |
other micro RNAs
|
| gptkbp:involved_in |
apoptosis
cell cycle regulation neurogenesis |
| gptkbp:is_associated_with |
poor prognosis
|
| gptkbp:is_expressed_in |
gptkb:Brain
gptkb:Heart ovary testis kidney liver pancreas placenta various tissues lung spleen |
| gptkbp:is_involved_in |
gptkb:diabetes
gptkb:neurodegenerative_diseases cellular homeostasis cellular metabolism developmental processes hypertension metabolic processes signal transduction autoimmune diseases chronic diseases metabolic syndrome obesity cardiovascular diseases cell signaling pathways cellular senescence infectious diseases tumor microenvironment cellular responses to stimuli gene expression regulation cellular signaling hyperlipidemia epigenetic regulation neoplasia cellular interactions response to stress |
| gptkbp:is_linked_to |
gptkb:Oncology
|
| gptkbp:is_located_in |
gptkb:chromosome_1
|
| gptkbp:is_regulated_by |
gptkb:p53
transcription factors |
| gptkbp:is_studied_for |
biomarker potential
|
| gptkbp:is_studied_in |
oncology research
|
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:located_in |
human genome
|
| gptkbp:part_of |
micro RNA family
|
| gptkbp:potential_therapeutic_target_for |
gptkb:cancer_treatment
|
| gptkbp:regulates |
cell cycle
gene expression stem cell properties |
| gptkbp:targets |
gptkb:SIRT1
gptkb:BCL2 gptkb:CDK6 multiple m RNAs |
| gptkbp:upregulated_by |
gptkb:p53
|