Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
infectious diseases
autoimmune diseases cancer immunology |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodes |
MHC class I proteins
|
| gptkbp:expressedIn |
all nucleated cells
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
present endogenous peptides
|
| gptkbp:hasPolymorphism |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
MHC class I genes
|
| gptkbp:importantFor |
immune surveillance
transplant rejection viral immunity |
| gptkbp:include |
gptkb:HLA-A
gptkb:HLA-B gptkb:HLA-C gptkb:HLA-E gptkb:HLA-F gptkb:HLA-G |
| gptkbp:involvedIn |
antigen presentation
|
| gptkbp:locatedIn |
gptkb:major_histocompatibility_complex
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6_(human)
|
| gptkbp:orthologIn |
mouse H-2 genes
|
| gptkbp:presentPeptidesTo |
cytotoxic T lymphocytes
|
| gptkbp:recognizedBy |
gptkb:CD8+_T_cells
|
| gptkbp:regulates |
cytokines
|
| gptkbp:structure |
alpha chain and beta-2 microglobulin
|
| gptkbp:bfsParent |
gptkb:MHC_class_I_molecules
|
| gptkbp:bfsLayer |
7
|