Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activeSiteResidue |
gptkb:His41
Cys145 |
| gptkbp:alternativeName |
gptkb:3CLpro
gptkb:nsp5 |
| gptkbp:biologicalProcess |
cysteine protease activity
|
| gptkbp:determines |
X-ray crystallography
|
| gptkbp:EC_number |
3.4.22.-
|
| gptkbp:foundIn |
gptkb:Middle_East_respiratory_syndrome_coronavirus
|
| gptkbp:function |
viral polyprotein processing
|
| gptkbp:gene |
ORF1ab
|
| https://www.w3.org/2000/01/rdf-schema#label |
MERS-CoV main protease
|
| gptkbp:inhibitedBy |
gptkb:GC376
peptidomimetic compounds |
| gptkbp:organism |
gptkb:Betacoronavirus
|
| gptkbp:orthologIn |
gptkb:SARS-CoV-2_main_protease
gptkb:SARS-CoV_main_protease |
| gptkbp:PDB |
4RSP
|
| gptkbp:requires |
viral replication
|
| gptkbp:sequence |
available in UniProt K9N7C7
|
| gptkbp:target |
antiviral drug development
|
| gptkbp:bfsParent |
gptkb:SARS-CoV-2_main_protease
|
| gptkbp:bfsLayer |
7
|