Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:MAP2K2
gptkb:Mitogen-activated_protein_kinase_kinase_2 |
| gptkbp:associatedWith |
gptkb:Noonan_syndrome-like_disorder
gptkb:Cardiofaciocutaneous_syndrome MEK1 gene |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodes |
gptkb:MEK2_protein
MAP2K2 protein |
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000126934
5605 |
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:function |
phosphorylates and activates ERK1/2
|
| gptkbp:HGNC_ID |
6844
|
| https://www.w3.org/2000/01/rdf-schema#label |
MEK2 gene
|
| gptkbp:involves |
gptkb:MAPK/ERK_pathway
|
| gptkbp:locatedOnChromosome |
gptkb:19p13.3
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:orthologInMouse |
gptkb:Map2k2
|
| gptkbp:proteinFamily |
dual specificity protein kinase
|
| gptkbp:regulates |
cell differentiation
cell proliferation cell survival |
| gptkbp:target |
gptkb:MEK_inhibitors
|
| gptkbp:UniProtID |
P36507
|
| gptkbp:bfsParent |
gptkb:MAP2K2_gene
|
| gptkbp:bfsLayer |
7
|