amine oxidase (flavin-containing) B
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:MAO-B
|
| gptkbp:associatedWith |
gptkb:Parkinson's_disease
|
| gptkbp:catalyzes |
oxidative deamination of amines
|
| gptkbp:cofactor |
gptkb:FAD
|
| gptkbp:component |
mitochondrial outer membrane
|
| gptkbp:EC_number |
1.4.3.4
|
| gptkbp:encodedBy |
gptkb:MAOB_gene
|
| gptkbp:Entrez_Gene_ID |
4129
|
| gptkbp:expressedIn |
brain
liver platelets |
| gptkbp:foundIn |
mitochondria
|
| gptkbp:function |
neurotransmitter metabolism
primary amine oxidase activity |
| gptkbp:GOProcess |
amine metabolic process
|
| https://www.w3.org/2000/01/rdf-schema#label |
amine oxidase (flavin-containing) B
|
| gptkbp:inhibitedBy |
gptkb:rasagiline
gptkb:selegiline gptkb:safinamide |
| gptkbp:locatedOnChromosome |
Xp11.3
|
| gptkbp:molecularWeight |
~58 kDa
|
| gptkbp:OMIM |
309860
|
| gptkbp:relatedTo |
gptkb:amine_oxidase_(flavin-containing)_A
|
| gptkbp:structure |
dimer
|
| gptkbp:substrate |
gptkb:benzylamine
phenylethylamine |
| gptkbp:UniProtID |
gptkb:P27338
|
| gptkbp:bfsParent |
gptkb:MAO-B
gptkb:monoamine_oxidase_B |
| gptkbp:bfsLayer |
7
|