Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:alsoKnownAs |
tumor necrosis factor-beta
|
| gptkbp:associatedWith |
autoimmune diseases
inflammatory diseases |
| gptkbp:discoveredIn |
1960s
|
| gptkbp:encodedBy |
gptkb:LTA_gene
|
| gptkbp:Entrez_Gene_ID |
4049
|
| gptkbp:formsComplexWith |
gptkb:Lymphotoxin-beta
|
| gptkbp:function |
mediates inflammation
induces cell death |
| gptkbp:gene |
gptkb:LTA
|
| gptkbp:HGNC_ID |
6720
|
| https://www.w3.org/2000/01/rdf-schema#label |
Lymphotoxin-alpha
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_superfamily
|
| gptkbp:molecularWeight |
25 kDa
|
| gptkbp:OMIM |
153440
|
| gptkbp:PDB |
gptkb:1TNR
|
| gptkbp:producedBy |
activated lymphocytes
|
| gptkbp:recipient |
gptkb:TNFR1
gptkb:TNFR2 |
| gptkbp:role |
apoptosis
immune response lymphoid organ development tumor regression |
| gptkbp:secretes |
gptkb:B_cells
gptkb:T_cells |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
homotrimer
heterotrimer with Lymphotoxin-beta |
| gptkbp:UniProtID |
P01374
|
| gptkbp:bfsParent |
gptkb:LTX-β
|
| gptkbp:bfsLayer |
7
|