|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:GBL
gptkb:GβL
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
protein binding
kinase binding
|
|
gptkbp:conservedIn
|
eukaryotes
|
|
gptkbp:encodes
|
Target of rapamycin complex subunit LST8
|
|
gptkbp:Entrez_Gene_ID
|
64223
ENSG00000103264
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
|
|
gptkbp:function
|
component of mTOR complex 1
component of mTOR complex 2
|
|
gptkbp:gene
|
gptkb:LST8
|
|
gptkbp:HGNC_ID
|
HGNC:17002
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LST8
|
|
gptkbp:interactsWith
|
gptkb:RICTOR
gptkb:mTOR
gptkb:RAPTOR
gptkb:SIN1
|
|
gptkbp:length
|
326
|
|
gptkbp:locatedOnChromosome
|
16
16p13.3
|
|
gptkbp:molecularWeight
|
37 kDa
|
|
gptkbp:OMIM
|
609196
|
|
gptkbp:orthologInYeast
|
Lst8p
|
|
gptkbp:pathway
|
gptkb:mTOR_signaling_pathway
|
|
gptkbp:proteinFamily
|
WD repeat-containing proteins
|
|
gptkbp:RefSeq
|
NM_020346
NP_065812
|
|
gptkbp:role
|
regulation of cell survival
regulation of autophagy
regulation of cell growth
regulation of metabolism
regulation of protein synthesis
|
|
gptkbp:structure
|
contains WD40 repeats
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:Q9BVC4
|
|
gptkbp:bfsParent
|
gptkb:MLST8
|
|
gptkbp:bfsLayer
|
7
|