Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:CD18
|
| gptkbp:component |
integrin family
|
| gptkbp:encodedBy |
gptkb:ITGB2_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
|
| gptkbp:formsComplexWith |
LFA-1 alpha chain
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
cell adhesion
integrin binding leukocyte migration |
| https://www.w3.org/2000/01/rdf-schema#label |
LFA-1 beta chain
|
| gptkbp:interactsWith |
gptkb:ICAM-1
gptkb:ICAM-2 gptkb:ICAM-3 |
| gptkbp:locatedOnChromosome |
chromosome 21q22.3
|
| gptkbp:molecularWeight |
~95 kDa
|
| gptkbp:partOf |
gptkb:LFA-1
|
| gptkbp:significance |
mutations cause leukocyte adhesion deficiency type 1
|
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:UniProtID |
P05107
|
| gptkbp:bfsParent |
gptkb:integrin_beta_2_(CD18)
|
| gptkbp:bfsLayer |
7
|