LDL receptor-related protein 6

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:abbreviation	gptkb:LRP6
gptkbp:alternativeSplicing	yes
gptkbp:associatedWith	coronary artery disease tooth agenesis bone density regulation
gptkbp:discoveredIn	1998
gptkbp:domain	EGF-like domain LDL-receptor class A domain YWTD repeat domain
gptkbp:encodedBy	gptkb:LRP6_gene
gptkbp:Entrez_Gene_ID	ENSG00000134970 40437
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	regulation of cell signaling co-receptor in Wnt signaling pathway
gptkbp:interactsWith	gptkb:Frizzled_receptors gptkb:Wnt_proteins
gptkbp:locatedOnChromosome	gptkb:chromosome_12p13.2
gptkbp:location	gptkb:plasma_membrane
gptkbp:molecularWeight	161 kDa
gptkbp:OMIM	603507
gptkbp:orthologIn	gptkb:Danio_rerio gptkb:Mus_musculus
gptkbp:phosphorylates	gptkb:GSK3β CK1γ
gptkbp:relatedTo	gptkb:Wnt/β-catenin_signaling gptkb:LDL_receptor_family
gptkbp:structure	single-pass type I membrane protein
gptkbp:UniProtID	O75581
gptkbp:bfsParent	gptkb:LRP6
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	LDL receptor-related protein 6