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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:WBSCR5
pp36
|
|
gptkbp:associatedWith
|
immunodeficiency
autoimmunity
|
|
gptkbp:discoveredBy
|
Weiss A et al.
|
|
gptkbp:discoveredIn
|
1998
|
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gptkbp:encodedBy
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gptkb:LAT_gene
|
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gptkbp:fullName
|
gptkb:Linker_for_activation_of_T_cells
|
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gptkbp:function
|
signal transduction
T cell activation
|
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gptkbp:gene
|
gptkb:LAT
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LAT (protein)
|
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gptkbp:interactsWith
|
gptkb:Grb2
gptkb:PLCĪ³1
gptkb:ZAP-70
gptkb:SLP-76
gptkb:Gads
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p11.2
|
|
gptkbp:location
|
gptkb:plasma_membrane
lipid rafts
|
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gptkbp:molecularWeight
|
36 kDa
|
|
gptkbp:mutationAssociatedWith
|
immune dysregulation
impaired T cell signaling
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:requires
|
T cell development
T cell activation
|
|
gptkbp:roleInPathway
|
gptkb:T_cell_receptor_signaling_pathway
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:structure
|
single-pass transmembrane protein
|
|
gptkbp:UniProtID
|
O43561
|
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gptkbp:bfsParent
|
gptkb:LAT
|
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gptkbp:bfsLayer
|
6
|