|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
JHDM3C
JMJD2C
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
chromatin modification
regulation of transcription
histone demethylase activity
|
|
gptkbp:cofactor
|
gptkb:2-oxoglutarate
Fe(II)
|
|
gptkbp:discoveredBy
|
Yamane et al.
|
|
gptkbp:discoveredIn
|
2006
|
|
gptkbp:domain
|
gptkb:Tudor_domain
PHD-type zinc finger
JmjC domain
|
|
gptkbp:encodes
|
KDM4C protein
|
|
gptkbp:Entrez_Gene_ID
|
9682
ENSG00000172057
|
|
gptkbp:expressedIn
|
gptkb:nucleus
|
|
gptkbp:fullName
|
Lysine Demethylase 4C
|
|
gptkbp:function
|
histone demethylase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0003677
GO:0032452
|
|
gptkbp:hasParalog
|
gptkb:KDM4B
KDM4A
KDM4D
|
|
gptkbp:HGNC_ID
|
HGNC:29000
|
|
gptkbp:involvedIn
|
epigenetic regulation
|
|
gptkbp:length
|
1064 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:9p24.1
|
|
gptkbp:molecularWeight
|
120 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:intellectual_disability
gptkb:autism_spectrum_disorder
schizophrenia
|
|
gptkbp:OMIM
|
609765
|
|
gptkbp:orthologInMouse
|
Kdm4c
|
|
gptkbp:overexpressedIn
|
gptkb:cancer
prostate cancer
esophageal squamous cell carcinoma
|
|
gptkbp:regulates
|
gene expression
chromatin structure
|
|
gptkbp:removesMethylationFrom
|
gptkb:H3K36me3
gptkb:H3K9me3
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:target
|
small molecule inhibitors
|
|
gptkbp:UniProtID
|
Q9H3R0
|
|
gptkbp:bfsParent
|
gptkb:9p24.1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KDM4C
|