|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:FBXL10
NDY1
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
cell cycle regulation
stem cell maintenance
epigenetic regulation
chromatin binding
oxidoreductase activity
|
|
gptkbp:demethylates
|
H3K36me2
H3K4me3
|
|
gptkbp:discoveredBy
|
2004
|
|
gptkbp:Entrez_Gene_ID
|
84678
ENSG00000140332
|
|
gptkbp:expressedIn
|
various tissues
hematopoietic cells
embryonic stem cells
|
|
gptkbp:fullName
|
gptkb:Lysine_Demethylase_2B
|
|
gptkbp:function
|
transcriptional regulation
histone demethylase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:28902
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KDM2B
|
|
gptkbp:interactsWith
|
gptkb:BCOR
gptkb:Polycomb_Repressive_Complex_1_(PRC1)
gptkb:RING1B
|
|
gptkbp:length
|
1336
|
|
gptkbp:locatedOnChromosome
|
12q24.31
|
|
gptkbp:molecularWeight
|
153 kDa
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
oncogenesis
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Kdm2b
|
|
gptkbp:pathway
|
chromatin modification
|
|
gptkbp:proteinFamily
|
PHD-type zinc finger
CXXC-type zinc finger
JmjC domain
|
|
gptkbp:regulates
|
cell proliferation
embryonic development
gene expression
cellular senescence
hematopoietic stem cell self-renewal
|
|
gptkbp:researchArea
|
cancer biology
epigenetics
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
Q8NHM5
|
|
gptkbp:bfsParent
|
gptkb:chromosome_12
|
|
gptkbp:bfsLayer
|
6
|