Lysine Demethylase 2B

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:FBXL10
JHDM1B
gptkbp:associatedWith gptkb:cancer
gptkbp:domain JmjC domain
F-box domain
CXXC zinc finger domain
gptkbp:Entrez_Gene_ID GC12M123456
gptkbp:enzymeCommissionNumber 1.14.11.-
gptkbp:function histone demethylase
gptkbp:gene gptkb:KDM2B
KDM2B gene
https://www.w3.org/2000/01/rdf-schema#label Lysine Demethylase 2B
gptkbp:interactsWith gptkb:BCOR
gptkb:RING1B
PCGF1
gptkbp:involves cell proliferation
stem cell maintenance
epigenetic regulation
transcriptional repression
gptkbp:locatedOnChromosome 12q24.31
gptkbp:molecularWeight 153 kDa
gptkbp:OMIM 609728
gptkbp:orthologInMouse Kdm2b
gptkbp:regulates gptkb:Polycomb_group_proteins
gene expression
cell cycle
gptkbp:removes_methyl_group_from dimethylated lysine 36 of histone H3 (H3K36me2)
gptkbp:species gptkb:Homo_sapiens
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID Q8NHM5
gptkbp:bfsParent gptkb:KDM2B
gptkbp:bfsLayer 7