Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:FBXL10
JHDM1B |
gptkbp:associatedWith |
gptkb:cancer
|
gptkbp:domain |
JmjC domain
F-box domain CXXC zinc finger domain |
gptkbp:Entrez_Gene_ID |
GC12M123456
|
gptkbp:enzymeCommissionNumber |
1.14.11.-
|
gptkbp:function |
histone demethylase
|
gptkbp:gene |
gptkb:KDM2B
KDM2B gene |
https://www.w3.org/2000/01/rdf-schema#label |
Lysine Demethylase 2B
|
gptkbp:interactsWith |
gptkb:BCOR
gptkb:RING1B PCGF1 |
gptkbp:involves |
cell proliferation
stem cell maintenance epigenetic regulation transcriptional repression |
gptkbp:locatedOnChromosome |
12q24.31
|
gptkbp:molecularWeight |
153 kDa
|
gptkbp:OMIM |
609728
|
gptkbp:orthologInMouse |
Kdm2b
|
gptkbp:regulates |
gptkb:Polycomb_group_proteins
gene expression cell cycle |
gptkbp:removes_methyl_group_from |
dimethylated lysine 36 of histone H3 (H3K36me2)
|
gptkbp:species |
gptkb:Homo_sapiens
|
gptkbp:subcellularLocation |
gptkb:nucleus
|
gptkbp:UniProtID |
Q8NHM5
|
gptkbp:bfsParent |
gptkb:KDM2B
|
gptkbp:bfsLayer |
7
|