|
gptkbp:instanceOf
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gptkb:protein
gptkb:gene
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|
gptkbp:alternativeName
|
gptkb:JHDM3B
gptkb:KDM4B
lysine demethylase 4B
|
|
gptkbp:amendedBy
|
gptkb:histone_H3
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:demethylates
|
gptkb:H3K36me3
gptkb:H3K9me3
|
|
gptkbp:domain
|
gptkb:Tudor_domain
PHD-type zinc finger
JmjC domain
|
|
gptkbp:encodedBy
|
KDM4B gene
|
|
gptkbp:Entrez_Gene_ID
|
23030
|
|
gptkbp:enzymeCommissionNumber
|
1.14.11.-
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:familyMember
|
Jumonji domain-containing proteins
|
|
gptkbp:firstDescribed
|
2004
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:hasBiologicalActivity
|
histone demethylase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
JMJD2B
|
|
gptkbp:interactsWith
|
gptkb:p53
estrogen receptor alpha
|
|
gptkbp:involvedIn
|
epigenetic regulation
transcriptional regulation
|
|
gptkbp:length
|
1096 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.3
|
|
gptkbp:molecularWeight
|
130 kDa
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
5F5U
5F5V
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
DNA damage response
estrogen receptor signaling
|
|
gptkbp:UniProtID
|
gptkb:O94953
|
|
gptkbp:upregulatedBy
|
gptkb:cancer
colorectal cancer
|
|
gptkbp:bfsParent
|
gptkb:KDM4B
|
|
gptkbp:bfsLayer
|
7
|