|
gptkbp:instanceOf
|
long-acting insulin analog
|
|
gptkbp:administeredBy
|
subcutaneous injection
|
|
gptkbp:administeredOnceDaily
|
yes
|
|
gptkbp:approvedBy
|
gptkb:FDA
2000
|
|
gptkbp:ATCCode
|
A10AE04
|
|
gptkbp:availableOn
|
solution for injection
|
|
gptkbp:biosimilar
|
yes
|
|
gptkbp:brand
|
gptkb:Basaglar
gptkb:Lantus
gptkb:Toujeo
|
|
gptkbp:CASNumber
|
160337-95-1
|
|
gptkbp:color
|
clear
|
|
gptkbp:contraindication
|
hypersensitivity to insulin glargine
|
|
gptkbp:countryOfOrigin
|
gptkb:France
|
|
gptkbp:developedBy
|
gptkb:Sanofi
|
|
gptkbp:duration
|
up to 24 hours
|
|
gptkbp:eliminatedIn
|
renal
|
|
gptkbp:halfLife
|
~12-19 hours
|
|
gptkbp:hasMolecularFormula
|
C267H404N72O78S6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Insulin glargine
|
|
gptkbp:legalStatus
|
Rx-only
|
|
gptkbp:marketedIn
|
gptkb:Asia
gptkb:Australia
gptkb:Canada
gptkb:Europe
gptkb:United_States
|
|
gptkbp:mechanismOfAction
|
regulates glucose metabolism
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:notForInsulinPump
|
yes
|
|
gptkbp:notForIVUse
|
yes
|
|
gptkbp:onset
|
1-2 hours
|
|
gptkbp:origin
|
recombinant DNA technology
|
|
gptkbp:patentExpired
|
yes
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:prescriptionStatus
|
prescription only
|
|
gptkbp:proteinBinding
|
low
|
|
gptkbp:routeOfAdministration
|
subcutaneous
|
|
gptkbp:sideEffect
|
gptkb:hypoglycemia
weight gain
injection site reactions
|
|
gptkbp:solubility
|
soluble in water
|
|
gptkbp:storage
|
refrigerated
|
|
gptkbp:usedFor
|
gptkb:diabetes_mellitus_type_2
diabetes mellitus type 1
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:insulin
|
|
gptkbp:bfsLayer
|
6
|