Insulin detemir

GPTKB entity

Statements (47)
Predicate Object
gptkbp:instanceOf long-acting insulin
gptkbp:approvalYear 2005
gptkbp:ATCCode A10AE05
gptkbp:brand gptkb:Levemir
gptkbp:CASNumber 169148-63-4
gptkbp:contraindication hypersensitivity to insulin detemir
gptkbp:developer gptkb:Novo_Nordisk
gptkbp:drugBank_ID DB01309
gptkbp:duration up to 24 hours
gptkbp:eliminationHalfLife 5-7 hours
gptkbp:form solution for injection
gptkbp:hasMolecularFormula C267H402N64O76S6
https://www.w3.org/2000/01/rdf-schema#label Insulin detemir
gptkbp:KEGGID D04566
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction insulin receptor agonist
gptkbp:metabolism gptkb:kidney
liver
gptkbp:notable_for lower risk of nocturnal hypoglycemia than NPH insulin
less weight gain than NPH insulin
gptkbp:origin genetically engineered yeast
gptkbp:pregnancyCategory B (US)
gptkbp:prescribes adults
children (age 2 and older)
gptkbp:prescriptionForm gptkb:cartoonist
vial
gptkbp:prescriptionRequired https://www.novo-pi.com/levemir.pdf
gptkbp:product recombinant DNA
gptkbp:proteinBinding >98%
gptkbp:PubChem_CID 16132451
CHEMBL1201587
gptkbp:riskFactor hypokalemia
allergic reactions
lipodystrophy
gptkbp:routeOfAdministration subcutaneous injection
gptkbp:sideEffect gptkb:hypoglycemia
weight gain
injection site reactions
gptkbp:solubility soluble in water
gptkbp:storage 2–8°C (refrigerated)
gptkbp:structureModification myristic acid attached to B29 lysine
gptkbp:synonym gptkb:NN304
gptkbp:UNII GFX7QIS1II
gptkbp:usedFor gptkb:type_2_diabetes
type 1 diabetes
gptkbp:bfsParent gptkb:insulin
gptkbp:bfsLayer 6