Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:pharmaceuticals
|
| gptkbp:administered_by |
Oral tablet
Liquid suspension Topical gel |
| gptkbp:available_in |
Liquid form
Gel form Tablet form |
| gptkbp:available_on |
Over-the-counter medication
Prescription medication |
| gptkbp:brand |
gptkb:Advil
gptkb:Motrin |
| gptkbp:casnumber |
15687-27-1
|
| gptkbp:category |
Category C
|
| gptkbp:chemical_formula |
C13 H18 O2
|
| gptkbp:contraindication |
Peptic ulcer disease
Severe liver disease Severe heart failure |
| gptkbp:discovered_by |
gptkb:Stewart_Adams
|
| gptkbp:discovery_year |
gptkb:1961
|
| gptkbp:dosage_form |
200-400 mg every 4-6 hours
1200 mg per day (OTC) 3200 mg per day (prescription) |
| gptkbp:excretion |
Urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ibuprofen
|
| gptkbp:interacts_with |
gptkb:Lithium
gptkb:ACE_inhibitors Diuretics Anticoagulants |
| gptkbp:mechanism_of_action |
Inhibition of cyclooxygenase (COX) enzymes
|
| gptkbp:metabolism |
Liver
|
| gptkbp:shelf_life |
3 years
|
| gptkbp:side_effect |
gptkb:Nausea
Dizziness Headache Stomach pain |
| gptkbp:storage |
Room temperature
Away from moisture |
| gptkbp:treatment |
Osteoarthritis
Rheumatoid arthritis Headaches Back pain Toothaches Muscle aches Fever in children Menstrual cramps Mild to moderate pain Postoperative pain |
| gptkbp:used_for |
Pain relief
Fever reduction Inflammation reduction |
| gptkbp:bfsParent |
gptkb:Fever
|
| gptkbp:bfsLayer |
4
|