PEDCQBHIVMGVHV-UHFFFAOYSA-N

URI: https://gptkb.org/entity/PEDCQBHIVMGVHV-UHFFFAOYSA-N
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf InChIKey
gptkbp:ATCCode M01AE01
gptkbp:bioavailability 80-100%
gptkbp:boilingPoint 157°C (decomposes)
gptkbp:CASNumber 15687-27-1
gptkbp:contraindication peptic ulcer
hypersensitivity to NSAIDs
severe heart failure
gptkbp:correspondsTo gptkb:Ibuprofen
gptkbp:discoveredBy gptkb:Stewart_Adams
gptkbp:eliminationHalfLife 1.8-2 hours
gptkbp:excretion gptkb:kidney
gptkbp:hasMolecularFormula C13H18O2
gptkbp:hasSMILES CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
gptkbp:hasTherapeuticUse analgesic
anti-inflammatory
antipyretic
gptkbp:hasUNII WK2XYI10QM
https://www.w3.org/2000/01/rdf-schema#label PEDCQBHIVMGVHV-UHFFFAOYSA-N
gptkbp:isApprovedDrug true
gptkbp:isNonsteroidalAntiInflammatoryDrug true
gptkbp:isOverTheCounterDrug true
gptkbp:isRacemicMixture true
gptkbp:IUPACName (RS)-2-(4-isobutylphenyl)propanoic acid
gptkbp:legalStatus OTC (over-the-counter)
gptkbp:meltingPoint 75-78°C
gptkbp:metabolism liver
gptkbp:molecularWeight 206.28 g/mol
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID gptkb:DB01050
gptkb:CHEMBL521
3672
gptkbp:routeOfAdministration oral
topical
intravenous
gptkbp:sideEffect nausea
dizziness
rash
gastrointestinal irritation
gptkbp:synonym gptkb:Nurofen
gptkb:Motrin
gptkb:Advil
gptkb:Brufen
gptkb:Ibuprofen
gptkbp:wasDiscoveredInYear 1961
gptkbp:wasFirstMarketedIn 1969
gptkbp:WHOModelListOfEssentialMedicines true
gptkbp:bfsParent gptkb:56-81-5
gptkb:Glycerol
gptkbp:bfsLayer 6